Lawrence Joseph
Bayesian statistics


Please Note: Prof. Joseph has retired.
These pages are left up in case they prove
useful, but the pages and software will
no longer be updated. All material and
software is "as is" with no guarantees
of functionality or correctness.
Bayesian Sample Size Change-point methods and applications Diagnostic testing
See related software		 Meta analysis Other topics
Complete CV
Research interests
Courses taught
Previous courses taught
EPIB-607 Principles of Inferential Statistics in Medicine
EPIB-613 Introduction to Statistical Software
EPIB-621 Data Analysis in the Health Sciences
EPIB-651 Bayesian Analysis in Medicine
EPIB-668 Introduction to Bayesian Analysis in the Health Sciences
EPIB-669 Intermediate Bayesian Analysis for the Health Sciences
EPIB-675 Bayesian Analysis in the Health Sciences
EPIB-682 Introduction to Bayesian Analysis in the Health Sciences
EPIB-683 Intermediate Bayesian Analysis for the Health Sciences
Publications
Methodological publications
Bayesian Sample Size
Change-point methods and applications
Diagnostic testing
Meta analysis
Other topics
Medical publications
Allergy and immunology
Asthma
Cardiology
Gastroenterology
Osteoporosis
Quality of Life
Rheumatology
Other
Book
Bayesian software
Bayesian Sample Size
Change-point methods and applications
Diagnostic testing
Diagnostic testing in Genetics
Links
Blouin B, Casapia M, Kaufman J, Joseph L, Larson C, Gyorkos T.
Bayesian methods for exposure misclassification adjustment in a mediation analysis: Hemoglobin and malnutrition in the association between Ascaris and IQ.
Epidemiology 2019 (epub ahead of print)
Lu Y, Joseph L, Bélisle P, Sawatwong P, Jatapai A, Whistler T, Thamthitiwat S, Paveenkittiporn W, Khemla S, Van Beneden C, Baggett H, Gregory C.
Pneumococcal pneumonia prevalence among adults with severe acute respiratory illness in Thailand - comparison of Bayesian latent class modeling and conventional analysis
BMC Infectious Diseases 2019;19:423:1-8
Blouin B, Casapia M, Joseph L, Gyorkos T.
A longitudinal cohort study of soil-transmitted helminth infections during the second year of life and long-term consequences on cognitive and verbal abilities
PLOS Neglected Tropical Diseases 2018;12(7):1-20
Blouin B, Casapia M, Joseph L, Kaufman J, Larson C, Gyorkos T.
The effect of cumulative soil-transmitted helminth infections over time on child development: A four-year longitudinal cohort study in preschool children using Bayesian methods to adjust for exposure misclassification
International Journal of Epidemiology 2018;47(4):1180-1194
Wang Z, Dendukuri N, Zar H, Joseph L.
Modeling conditional dependence among multiple diagnostic tests
Statistics in Medicine 2017;36:4843-4859
Oskoui M, Ng P, Dorais M, Pigeon N, Koclas L, Lamarre C, Malouin F, Richards C, Shevell M, Joseph L.
Accuracy of administrative claims data for Cerebral Palsy: A retrospective cohort study
CMAJ Open 2017;5(3):E570-E575
Wang Z, Dendukuri N, Joseph L.
Understanding the effects of conditional dependence in research studies involving imperfect diagnostic tests
Statistics in Medicine 2017;36(3):466-480
Lu Y, Baggett H, Rhodes J, Thamthitiwat S, Joseph L, Gregory C.
Bayesian latent class estimation of the incidence of chest radiograph-confirmed pneumonia in rural Thailand
Epidemiology and Infection 2016;144(13):2858-2865
Schumacher S, van Smeden M, Dendukuri N, Joseph L, Moons K, Nicol M, Pai M, Zar H.
Diagnostic test accuracy in childhood pulmonary tuberculosis: a Bayesian latent class analysis
American Journal of Epidemiology 2016;84(9):690-700
Bernatsky S, Smargiassi A, Barnabe C, Svenson L, Brand A, Martin R, Hudson M, Clarke A, Fortin P, van Donkelaar A, Edworthy S, Bélisle, Joseph L.
Fine particulate air pollution and systemic autoimmune rheumatic disease in two Canadian provinces
Environmental Research 2016;146:85-91
Smallwood M, Vijh R, Nauche B, Lebouche, B Joseph L, Pai N.
Evaluation of a rapid point of care test for detecting acute HIV infection, and examining the role of study quality on diagnostic accuracy: a Bayesian meta-analysis
PLOS ONE 2016;11(2):1-13
Postuma R, Berg D, Adler C, Bloem B, Chan P, Dubois B, Gasser T, Goetz C, Halliday G, Hardy J, Joseph L, Lang A, Liepelt-Scarfone I, Litvan I, Marek K, Obeso J, Oertel W, Olanow W, Poewe W, Stern M, Deuschl G.
MDS Research Criteria for Prodromal Parkinson's Disease
Movement Disorders 2015;30(12):1591-1599
Vinet E, Pineau C, Clarke A, Scott S, Fombonne E, Joseph L, Platt R, Bernatsky S.
Increased risk of autism spectrum disorders in children born to women with systemic lupus erythematosus: Results from the OSLER Cohort
Arthritis & Rheumatology 2015;67(12):3201-3208
Carabin H, McGarvey S, Sahlu I, Tarafder M, Joseph L, Andrade B, Balolong E, Olveda R.
Schistosoma japonicum in Samar, the Philippines: infection in dogs and rats as possible a risk factor for human infection.
Epidemiology and Infection 2015;38(3):1767-1776-
Laliberté V, Joseph L, Gold I.
A Bayesian latent class model for estimating the prevalence of schizophreniain the Province of Quebec using administrative data.
Frontiers in Psychiatry 2015;6(99):1-7
Bernatsky S, Smargiassi A, Johnson M, Kaplan G, Barnabe C, Svenson L, Brand A, Bertazzon S, Hudson M, Clarke A, Fortin P, Edworthy S, Bélisle P, Joseph L.
Fine particulate air pollution, nitrogen dioxide, and systemic auto-immune rheumatic disease in Calgary, Alberta
Environmental Research 2015;140:474-478
Soller L, Ben-Shoshan M, Harrington D, Knoll M, Fragapane J, Joseph L, St.-Pierre Y, La Vieille S, Wilson K, Elliott S, Clarke A.
Adjusting for non-response bias corrects overestimates of food allergy prevalence.
Journal of Allergy and Clinical Immunology: In Practice 2015;3(2):291-293
Shiff N, Lix L, Oen K, Joseph L, Duffy C, Stringer E, Tucker L, Svenson L, Bélisle P, Bernatsky S.
Chronic inflammatory arthritis prevalence estimates for children and adolescents in three Canadian provinces
Rheumatology International 2015;35(2):345-350
Shiff N, Lix L, Joseph L, Duffy C, Tucker L, Svenson L, Bélisle P, Bernatsky S.
The prevalence of systemic autoimmune rheumatic diseases in Canadian pediatric populations: Administrative database estimates
Rheumatology International 2014;35(3):569-573
Bernatsky S, Dekis A, Hudson M, Pineau C, Boires G, Fortin P, Bessette L, Jean S, Chetaille A, Bélisle P, Bergeron L, Feldman D, Joseph L.
Rheumatoid arthritis prevalence in Quebec
BMC Research Notes 2014;7(1):937
Pai N, Dhurat R, Potter M, Behlim T, Savard P, Landry G, Vadnais C, Joseph L.
Will a quadruple multiplexed point-of-care screening strategy for HIV related co-infections be feasible and impact detection of new co-infections in at risk populations? Results from cross-sectional studies
BMJ Open 2014;4(12):1-9
Broten L, Lacaille D, Avina-Zubieta J, Joseph L, Hanly J, Peschken C, Lix L, Svenson L, O'Donnell S, Jean S, Pineau C, Clarke A, Fortin P, Smith M, Bélisle P, Hudson M, Badley E, Bergeron L, Bernatsky S.
Systemic autoimmune rheumatic disease prevalence in Canada: Updated analyses across seven provinces
The Journal of Rheumatology 2014;41(4):673-679
de Champlain F, Boothroyd L, Vadeboncœur A, Huynh T, Nguyen V, Eisenberg M, Joseph L, Boivin J, Segal E.
Computerized interpretation of the prehospital electrocardiogram: predictive value for ST-segment elevation myocardial infarction and impact on on-scene time
Canadian Journal of Emergency Medicine 2014;16(2):94-105
Sewitch M, Jiang M, Joseph L, Hilsden R, Bitton A.
Developing model-based algorithms to identify screening colonoscopies using administrative health databases
BMC Medical Informatics and Decision-Making 2013;13(45):1-7
Jafari Y, Peeling R, Shivkumar S, Lambert G, Claessens C, Cajas J, Lambert G, Joseph L, Pai N.
Are Treponema pallidum specific rapid and point-of-care tests for syphilis accurate enough for screening in resource limited settings? Evidence from a meta-analysis.
PLoS ONE 2013;8(2):1-8
Oskoui M, Joseph L, Dagenais L, Shevell M.
Prevalence of cerebral palsy in Quebec: Alternative approaches.
Neuroepidemiology 2013;40:264-268
Speybroeck N, Devleesschauwer B, Joseph L, Berkvens D.
Misclassification errors in prevalence estimation: Bayesian handling with care
International Journal of Public Health 2013;58(5):791-795
Dendukuri N, Schiller I, Joseph L, Pai M.
Bayesian meta-analysis of the accuracy of a test for tuberculous pleuritis in the absence of a gold-standard reference.
Biometrics 2012;68(4):1285-1293
Barnabe C, Joseph L, Bélisle P, Labrecque J, Edworthy S, Barr S, Fritzler M, Svenson L, Hemmelgarn B, Bernatsky S.
Prevalence of autoimmune inflammatory myopathy in Alberta’s First Nations population
Arthritis Care and Research 2012;64(11):1715-1719
Jiang M, Sewitch MJ, Joseph L, Barkun A.
Different screening definitions have little impact on polypectomy rate estimates.
Canadian Journal of Gastroenterology 2012;26(11):791-794
Sewitch M, Hilsden R, Joseph L, Rabeneck L, Paszat L, Bitton A, Cooper M.
Qualitative study of physician perspectives on classifying screening and non-screening colonoscopy using administrative health data: adding practice does not make perfect
Canadian Journal of Gastroenterology 2012;12:889-893
Barnabe C, Joseph L, Bélisle P, Labrecque J, Edworthy S, Barr S, Fritzler M, Svenson L, Hemmelgarn B, Bernatsky S.
Prevalence of systemic lupus erythematosus and systemic sclerosis in Alberta's First Nations population
Arthritis Care and Research 2012;64(1):138-143
Ladouceur M, Rahme E, Scott A, Schwartzman K, Joseph L.
Modeling continuous diagnostic test data using approximate Dirichlet process distributions
Statistics in Medicine 2011;30(21):2648-2662
Bernatsky S, Lix L, Hanly J, Hudson M, Badley E, Peschken C, Pineau C, Clarke A, Fortin P, Smith M, Bélisle P, Lagace C, Bergeron L, Joseph L.
Surveillance of systemic autoimmune rheumatic diseases using administrative data
Rheumatology International 2011;31(4):549-554
Tarafder M, Carabin H, McGarvey S, Joseph L, Balolong E, Olveda R.
Assessing the impact of measurement error on an epidemiological association between two helminthic infections
PLOS Neglected Tropical Diseases 2011;5(3):1-7
Lu Y, Dendukuri N, Schiller I, Joseph L.
A Bayesian approach to simultaneously adjusting for verification bias and reference standard bias in diagnostic test studies
Statistics in Medicine 2010;29(24):2532-2543
Tarafder M, Carabin H, Joseph L, Balolong E, Olveda R, McGarvey S.
Estimating the sensitivity and specificity of Kato-Katz stool examination technique for detection of hookworms, Ascaris lumbricoides, and Trichuris trichiura infections in humans in the absence of a gold standard
International Journal for Parasitology 2010;40(4):399-404
Weichenthal S, Joseph L, Bélisle P, Dufresne A.
Bayesian estimation of the probability of asbestos exposure from lung fibre counts
Biometrics 2010;66(2):603-612
Bernatsky S, Joseph L, Pineau C, Bélisle P, Lix, L, Banerjee D, Clarke A.
Polymyalgia rheumatic prevalence in a population-based sample
Arthritis Care and Research 2009;61(9):1264-1267
Bernatsky S, Joseph L, Pineau C, Bélisle P, Hudson M, Clarke A.
Scleroderma prevalence: Demographic variations in a population-based sample
Annals of the Rheumatic Diseases 2009;61(3):400-404
Scott A, Joseph L, Bélisle P, Behr M, Schwartzman K.
Bayesian estimation of tuberculosis clustering rates from DNA sequence data
Statistics in Medicine 2008;27(1):140-156
Ladouceur M, Rahme E, Pineau C, Joseph L.
Robustness of prevalence estimates derived from misclassified data from administrative databases
Biometrics 2007;63:272-279
Benitoa A, Carmena D, Joseph L, Martineza J, Guisantesa J.
Dog echinococcosis in northern Spain: comparison of coproantigen and serum antibody assays with coprological exam
Veterinary Parasitology 2006;142:102-111
Bernatsky S, Joseph L, Bélisle P, Boivin J, Rajan R, Moore A, Clarke A.
A Bayesian hierarchical model for estimating the properties of cancer ascertainment methods in cohort studies
Statistics in Medicine 2005;24:2365-2379
Carabin H, Marshall C, Joseph L, Riley S, Olveda R, McGarvey S.
Estimating and modelling the dynamics of the intensity of infection with Schistosoma japonicum in villagers of Leyte, Philippines. Part I: A Bayesian cumulative logit model
American Journal of Tropical Medicine and Hygiene 2005;72(6):745-753
Carabin H, Balolong E, Joseph L, McGarvey S, Johansen M, Fernandez T, Willingham A, Olveda R.
Estimating sensitivity and specificity of a faecal examination method for Schistosoma japonicum infection in cats, dogs, water buffaloes, pigs and rats in Western Samar and Sorsogon Provinces, The Philippines
International Journal of Parasitology 2005;35:1517-1524
Dendukuri N, Joseph L.
Bayesian approaches to modeling the conditional dependence between multiple diagnostic tests
Biometrics 2001;57(1):158-167
Rahme E, Joseph L.
Estimating the prevalence of a rare disease: adjusted maximum likelihood
The Statistician 1998;47(1):149-158
Demissie K, White N, Joseph L, Ernst P.
Bayesian estimation of asthma prevalence, and comparison of exercise and questionnaire diagnostics in the absence of a gold standard
Annals of Epidemiology 1998;8(3):201-208
Hajian-Tilaki K, Hanley J, Joseph L, Collet J-P.
A comparison of parametric and non-parametric approaches to ROC analysis of the accuracy of quantitative diagnostic tests
Medical Decision Making 1997;17(1):94--102
Hajian-Tilaki K, Hanley J, Joseph L, Collet J-P.
An extension of Receiver Operating Characteristic analysis to data concerning multiple signal detection tasks
Academic Radiology 1997;4(3):222-229
Joseph L, Gyorkos T.
Inferences for likelihood ratios in the absence of a gold standard
Medical Decision Making 1996;16(4):412--417
Joseph L, Gyorkos T, Coupal L.
Bayesian estimation of disease prevalence and the parameters of diagnostic tests in the absence of a gold standard
American Journal of Epidemiology 1995;141(3):263-272