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Link to PubMed list of our publications
Park F. Cho, Francis Poulin, Yoon Andrew Cho-Park, Ian B. Cho-Park, Jarred D. Chicoine, Paul Lasko and Nahum Sonenberg A New Paradigm for Translational Control: Inhibition via 5'-3' mRNA Tethering by Bicoid and the eIF4E Cognate 4EHP Cell. 2005 May 6;121(3):411-23.
Regulation of cap-dependent translation by eIF4E inhibitory proteins. Kahvejian A, Svitkin YV, Sukarieh R, M'Boutchou MN, Sonenberg N. Mammalian poly(A)-binding protein is a eukaryotic translation initiation
factor, which acts via multiple mechanisms. Costa-Mattioli
M, Svitkin Y, Sonenberg N. La autoantigen is necessary for optimal function of the
poliovirus and hepatitis C virus internal ribosome entry site in vivo and in
vitro. Ferraiuolo MA, Lee CS, Ler LW,
Hsu JL, Costa-Mattioli M, Luo
MJ, Reed R, Sonenberg N. A nuclear
translation-like factor eIF4AIII is recruited to the mRNA during splicing and
functions in nonsense-mediated decay. An efficient
system for cap- and poly(A)-dependent translation in
vitro. Roy
G, Miron M, Khaleghpour K, Lasko P, Sonenberg N. The
Drosophila poly(A) binding protein-interacting
protein, dPaip2, is a novel effector of cell growth. Structural
basis of ligand recognition by PABC, a highly
specific peptide-binding domain found in poly(A)-binding
protein and a HECT ubiquitin ligase. Miron M, Lasko P, Sonenberg N. Signaling
from Akt to FRAP/TOR targets both 4E-BP and S6K in
Drosophila melanogaster. Poulin F, Brueschke A, Sonenberg N. Gene fusion and overlapping reading frames in the mammalian genes for
4E-BP3 and MASK. Gradi A, Svitkin YV, Sommergruber W, Imataka H, Morino S, Skern T, Sonenberg N. Human
rhinovirus 2A proteinase cleavage sites in eukaryotic
initiation factors (eIF) 4GI and eIF4GII are
different. Brasey A, Lopez-Lastra M, Ohlmann T, Beerens N, Berkhout B, Darlix JL, Sonenberg N. The leader of
human immunodeficiency virus type 1 genomic RNA
harbors an internal ribosome entry segment that is active during the G2/M phase
of the cell cycle. Tan SL, Pause A, Shi Y, Sonenberg
N. Hepatitis C
therapeutics: current status and emerging strategies. Deng
J, Harding HP, Raught B, Gingras
AC, Berlanga JJ, Scheuner
D, Kaufman RJ, Ron D, Sonenberg N. Activation of
GCN2 in UV-irradiated cells inhibits translation. Roy
G, De Crescenzo G, Khaleghpour
K, Kahvejian A, O'Connor-McCourt M, Sonenberg N. Paip1
interacts with poly(A) binding protein through two
independent binding motifs. Lachance PE, Miron M, Raught B, Sonenberg N, Lasko P. Phosphorylation of eukaryotic translation initiation factor 4E is critical for growth. Svitkin YV, Imataka H, Khaleghpour K, Kahvejian A, Liebig HD, Sonenberg N. Hierarchical phosphorylation of the translation
inhibitor 4E-BP1. Adipose tissue reduction in mice lacking the translational inhibitor
4E-BP1. Evdokimova V, Ruzanov P, Imataka H, Raught B, Svitkin Y, Ovchinnikov LP, Sonenberg N. The major
mRNA-associated protein YB-1 is a potent 5' cap-dependent mRNA stabilizer. Pyronnet S, Dostie J, Sonenberg N. Suppression of cap-dependent translation in mitosis. Protein synthesis. The perks of balancing glucose. Dual
interactions of the translational repressor Paip2 with poly(A)
binding protein. Miron M, Verdu J, Lachance PE, Birnbaum MJ, Lasko PF, Sonenberg N. The
translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling
and cell growth in Drosophila. Svitkin YV, Pause A, Haghighat A,
Pyronnet S, Witherell G, Belsham GJ, Sonenberg N. The requirement
for eukaryotic initiation factor 4A (elF4A) in translation is in direct
proportion to the degree of mRNA 5' secondary structure. Khaleghpour K, Svitkin YV, Craig
AW, DeMaria CT, Deo RC,
Burley SK, Sonenberg N. Translational
repression by a novel partner of human poly(A) binding
protein, Paip2. Wakiyama M, Imataka H, Sonenberg N. Interaction
of eIF4G with poly(A)-binding protein stimulates
translation and is critical for Xenopus oocyte maturation. Pyronnet S, Pradayrol L, Sonenberg N. A cell cycle-dependent internal ribosome entry site. Dostie J, Ferraiuolo M, Pause A,
Adam SA, Sonenberg N. A novel
shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding
protein, eIF4E. Raught B, Gingras AC, Gygi SP, Imataka H, Morino S, Gradi A, Aebersold R, Sonenberg N. Serum-stimulated,
rapamycin-sensitive phosphorylation
sites in the eukaryotic translation initiation factor 4GI. Dostie J, Lejbkowicz F, Sonenberg N. Nuclear
eukaryotic initiation factor 4E (eIF4E) colocalizes
with splicing factors in speckles. Morino S, Imataka H, Svitkin YV, Pestova TV, Sonenberg N. Eukaryotic
translation initiation factor 4E (eIF4E) binding site and the middle one-third
of eIF4GI constitute the core domain for cap-dependent translation, and the
C-terminal one-third functions as a modulatory
region. |
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