Mark Goldberg, PhD

Professor, Department of Medicine, McGill University

Division of Clinical Epidemiology, McGill University Health Center

Department of Epidemiology and Biostatistics

Tel: (514) 934-1934, ext. 36917


Web page:

Environmental epidemiology group:

New Papers 2019-2020

Villeneuve PJ, Goldberg MS. Methodological considerations for epidemiological studies of air pollution and the SARS and COVID-19 coronavirus outbreaks. Env Health Perspect 2020; 128:95001.

     This paper explains the methodological deficiencies and inherent biases in unpublished and published studies of  associations bewteen air pollution and mortality and other sequela from SARS and COVID-19. 

Zhang H, Ahearn TU, Lecarpentier J, Barnes D, Beesley J, Qi G, et al. 2020. Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. Nat Genet 52:572-581.

Feng H, Gusev A, Pasaniuc B, Wu L, Long J, Abu-full Z, et al. 2020. Transcriptome-wide association study of breast cancer risk by estrogen-receptor status. Genetic Epidemiology 44:442-468.

Liu J, Prager-van der Smissen WJC, Collée JM, Bolla MK, Wang Q, Michailidou K, et al. 2020. Germline hoxb13 mutations p.G84e and p.R217c do not confer an increased breast cancer risk. Sci 10:9688.

Shin S, Bai L, Oiamo TH, Burnett RT, Weichenthal S, Jerrett M, et al. 2020. Association between road traffic noise and incidence of diabetes mellitus and hypertension in toronto, canada: A population-based cohort study. Journal of the American Heart Association 9:e013021.

Fachal L, Aschard H, Beesley J, Barnes DR, Allen J, Kar S, et al. 2020. Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. Nature Genetics 52:56-73.

Dork, T., et al. (2019). "Two truncating variants in FANCC and breast cancer risk." Sci Rep 9(1): 12524.

Figlioli, G., et al. (2019). "The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer." NPJ Breast Cancer 5: 38.

Paul, L. A., et al. (2019). "The impact of air pollution on the incidence of diabetes and survival among prevalent diabetes cases." Environ Int 134: 105333.

Fachal, L. et al. “Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes”. Nature Genetics,

Mark S. Goldberg, Paul J. Villeneuve, Dan Crouse, Teresa To, Scott A Weichenthal, Claus Wall, Anthony B. Miller. Associations between incident breast cancer and ambient concentrations of nitrogen dioxide from a national land use regression model in the Canadian National Breast Screening Study. Environment International, 133, Part B, December 2019, 105182.

Shin, S.  Ambient Air Pollution and the Risk of Atrial Fibrillation and Stroke: A Population-Based Cohort Study. Environmental Health Perspectives, 2019; 127(8), 87009.

Bai et al., Exposure to ambient air pollution and the incidence of congestive heart failure and acute myocardial infarction: A population-based study of 5.1 million Canadian adults living in Ontario. Environment International 2019;132: (2019) 105004

Li, S., et al. Exposure–Response Associations of Household Air Pollution and Buccal Cell Telomere Length in Women Using Biomass Stoves. Environmental Health Perspectives, 2019; 127(8): 87004

Bai, L., et al. (2019). "Exposure to ambient air pollution and the incidence of lung cancer and breast cancer in the Ontario Population Health and Environment Cohort." Int J Cancer.

Jiang, X., et al. (2019). "Shared heritability and functional enrichment across six solid cancers." Nat Commun 10(1): 431.

Ferreira, M. A., et al. (2019). "Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer." Nat Commun 10(1): 1741.

Mavaddat, N., et al. (2019). "Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes." Am J Hum Genet 104(1): 21-34.


Ecological economics

I am proud to announce a new book ecological  economics that I contributed three chapters. This is the result of a project that was lead by Prof. Peter Brown, McGill, and funded by SSHRC. Edited by Peter Brown and Peter Timmerman, York University. Published by Columbia University Press, September 2015.

Chapter 4. Measurement of essential indicators in ecological economics. By Mark S. Goldberg and Geoffrey Garver.

Chapter 5. Boundaries and Indicators:  Conceptualizing and Measuring Progress Toward an Economy of Right Relationship Constrained by Global Ecological Limits. By Mark S. Goldberg and Geoffrey Garver.

Chapter 6. Revisiting the metaphor of human health for assessing ecological systems and its application to ecological economics. By Mark S. Goldberg, Geoffrey Garver, Nancy E. Mayo.

Selected recent studies on air pollution and health

Shin, S., et al. (2018). "Effects of ambient air pollution on incident Parkinson's disease in Ontario, 2001 to 2013: a population-based cohort study." Int J Epidemiol 47(6): 2038-2048.

Paul J. Villeneuve, Mark S. Goldberg, Dan L. Crouse, Teresa To, Scott A. Weichenthal, Claus Wall, Anthony B. Miller. Residential exposure to fine particulate matter air pollution and incident breast cancer in a cohort of Canadian women. Environmental Epidemiology (2018) 2:e021

Bai, L., et al. (2018). "Long-term exposure to air pollution and the incidence of multiple sclerosis: A population-based cohort study." Environ Res 166: 437-443.

Mark S. Goldberg, France Labrèche, Scott Weichenthal, Eric Lavigne, Marie-France Valois, Marianne Hatzopoulou, Maryam Shekarrizfard. Number Concentrations of Ultrafine Particles and the Incidence of Postmenopausal Breast Cancer. Environ Epidemiology, 2018 1:e006.

Stephane Buteau, Mark S. Goldberg, Richard T. Burnett, Antonio Gasparrini, Marie-France Valois, James M. Brophy, Dan L. Crouse, Marianne Hatzopoulou. Associations between ambient air pollution and daily mortality in a cohort of congestive heart failure: Case-crossover and nested case-control analyses using a distributed lag nonlinear model. Environ International, 2018; 113 313-324 (doi:

Chen, H., et al. (2017). "Exposure to ambient air pollution and the incidence of dementia: A population-based cohort study." Environ Int 108: 271-277.

Mark S. Goldberg, France Labrèche, Scott Weichenthal, Eric Lavigne, Marie-France Valois, Marianne Hatzopoulou, Keith Van Ryswyk, Maryam Shekarrizfard,P aul J. Villeneuve, Daniel Crouse, Marie-Élise Parent. The association between the incidence of postmenopausal breast cancer and concentrations at street-level of nitrogen dioxide and ultrafine particles. Environmental Research 158 (2017) 7–15.

Weichenthal, S. et al. Spatial variations in ambient ultrafine particle concentrations and the risk of incident prostate cancer: A case-control study. Environmental Research 156 (2017) 374–380

Buteau, S., et al. (2017). Comparison of spatiotemporal prediction models of daily exposure of individuals to ambient nitrogen dioxide and ozone in Montreal, Canada. Env Res 156:201-230

Chen, H., Burnett, R.T., Copes, R., Kwong, J.C., Villeneuve, P.J., Goldberg, M.S., Brook, R.D., van Donkelaar, A., Jerrett, M., Martin, R.V., Kopp, A., Brook, J.R., and Tu, J.V. Ambient fine particulate matter and mortality among survivors of myocardial infarction: population-based cohort study. Environmental Health Perspectives, 2016; doi: 10.1289/EHP185

Godri Pollitt, K. J., et al. (2016). "Trace metal exposure is associated with increased exhaled nitric oxide in asthmatic children." Environ Health 15(1): 94.

Effects of weather on health and climate change

Bai, L., et al. (2016). "Hospitalizations from Hypertensive Diseases, Diabetes, and Arrhythmia in Relation to Low and High Temperatures: Population-Based Study." Sci Rep 6: 30283.

Vutcovici et al. Effects of diurnal variations in temperature on non-accidental mortality among the elderly population of Montreal, Quebec, 1984-2007. Int J Biometeorol 2013;  DOI: 10.1007/s00484-013-0664-9

Goldberg et al.  The short-term influence of temperature on daily mortality in the temperate climate of Montreal, Canada. Environmental Research, 2011;111:853–860 

Smargiassi et al. Variation of daily warm season mortality as a function of micro-urban heat islands, Journal of Epidemiology and Community Health 2009;63:659–664

Climate change is a real and present danger  


The dangers of hydrofracking

Philips S, Goldberg MS.  Natural Gas Development: Extracting Externalities – Towards Precaution-Based Decision-Making. McGill International Journal of Sustainable Development Law & Policy. 2013; 8(2): 151-204.

Selected recent publications on occupational cancer

Aude Lacourt, France Labrèche, Mark S. Goldberg, Jack Siemiatycki, Jérôme Lavoué. Agreement in Occupational Exposures Between Men and Women Using Retrospective Assessments by Expert Coders. Annals of Work Exposures and Health, 2018, 1–12.

Sauve, J. F., et al. (2018). "Development of and Selected Performance Characteristics of CANJEM, a General Population Job-Exposure Matrix Based on Past Expert Assessments of Exposure." Annals of Work Exposures and Health, 2018, Vol. 62, No. 7, 783–795.

France Labrèche, Mark S. Goldberg, Dana Hashim, and Elisabete Weiderpass, “Breast Cancer”, in Occupational Cancers, second edition. Springer, 2020. Sisko Anttila and Paolo Boffetta, editors. Chapter 24. p.417-438.

Labrèche et al. Postmenopausal breast cancer and occupational exposures. Occup and Environ Med 2010;67:263-9. 


Medical Uses of Statistics (2009), edited by John C. Bailar and David C. Hoaglin. I have two chapters in this book, as does Prof. Nancy Mayo, Division of Clinical Epidemiology. It is published by John Wiley and sponsored by the New England journal of Medicine.

© Mark Goldberg 2020